Q&A: Understanding protein mutations that affect gene expression to drive cancer progression
Graphic abstract. Credit: Cell genomics (2024). DOI: 10.1016/j.xgen.2024.100537 Graduate student Hillary Layden studies transcriptional control in cancer in the lab of Scott Hiebert, the Hortense B. Ingram Chair in Cancer Research and professor of biochemistry. Below, Layden shares results from her research in which she used deep genomic analysis to determine how protein mutations affect…